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ProductOverview
Transcriptionalfactors,OCT3/4(POU5F1)andSTAT3functionaskeyregulatorsinmaintainingpluripotencyofstemcells.Thus,POU5F1andSTAT3havebeenwidelyusedasmolecularMarkersofpluripotentialstemcells.Pluripotentialcell-specificNanoggeneisanewlyidentifiedhomeodomain-bearingtranscriptionalfactor.Importantly,Nanogisexpressedspecifictoearlyembryosandpluripotentialstemcellsincludingmouseandhumanembryonicstem(ES)andembryonicgerm(EG)cells.Itisakeymoleculeinvolvedinthesignalingpathwayformaintainingthecapacityforself-renewalandpluripotency,bypassingregulationbytheSTAT3pathway.Therefore,Nanogisoneofthemolecularmarkerssuitableforrecognizingtheundifferentiatedstateofstemcellsinthemouseandhuman.
ProductSpecifications
Size
200mLor100mL
StorageandStABIlity
Storeat 4C(shortterm),-20°Cor-80C(longterm),stablefor3yearswhenstoredasdirected.
QualityControl
Host:Rabbit
Immunogen: HumanNanogpeptide
Clonality:Polyclonal
Purity:Immunogenaffinitypurified
Concentration:0.2mg/mL
StorageBuffer:PBS(incl.0.1%sodiumazide)
NotetoPurchaser
Thisproductisforresearchuseonly,notfortherapeuticordiagnosticpurposes.ItisnotallowedtosellthisproducttoathirdpartyoruseitforcommercialpurposeswithoutpermissionfromReproCELL.
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